This intensive half-day workshop will provide participants with a solid foundation in DNA methylation analyses for human population studies. Using hands-on R lab sessions, this workshop will integrate important conceptual and study design considerations where participants will work with real methylation data generated by the Illumina Infinium MethylationEPIC (850k) BeadChip platform. Participants will learn data handling, quality control, and basic analysis of DNA methylation data for epigenome-wide association studies (EWAS), including epigenetic clocks and regional analyses. Participants should leave this course prepared to undertake basic EWAS analyses. A working knowledge of R programming and basic knowledge of biostatistics are recommended for this course.
Download the IGSS_Epigenetics_Course_2021.zip file to your computer's desktop. Extract the contents to a folder on your hard drive. Run the "IGSS_2021_install_packages FINAL.r" script. It can take up to a couple of hours to install all the necessary R packages, so please allow plenty of time before the workshop. We also recommend that you have ~4G of RAM available for the analyses.