14th Annual IGSS Conference • October 20-21, 2023

Integrating Genetics and the Social Sciences 2023

Time	Event
8:30-9:00	Coffee and Pastries
9:00-12:00	Statistical Genetics Workshop
Qiongshi Lu Frontiers of PGS Construction, Optimization, and Use in the Social Sciences
12:00-1:00	Lunch
1:00-2:00	Session 1: Polygenic Indices Methods and Applications
Robel Alemu Relative predictive performance of polygenic indexes (PGIs) across diverse ancestral populations
Silvia Helena Barcellos Early-Life Determinants of Cognitive Decline and Dementia: The Role of Genetics and Education
Aysu Okbay Polygenic Index Repository v2
2:00-2:15	Break
2:15-3:15	Session 2: Statistical Genetics Methods
Titus Galama GWAS 2.0 – Correcting for volunteer bias in GWAS uncovers novel genetic variants and increases heritability estimates
Zhongxuan Sun Pervasive biases in GWAS using family history of Alzheimer's disease as proxy phenotypes
Ramina Sotoudeh Are we over-controlling for population stratification and discounting causal effects of genetic ancestry?
3:15-3:30	Break
3:30-4:30	Session 3: Frontiers in the Field of Genetics and Social Sciences
Jennifer Momkus Socioepigenomics of Cellular Immunosenescence in Adulthood: The Add Health Study
Amadou Gaye Transcriptome footprint of dietary sodium intake in African Americans
Jiacheng Miao Quantifying and interpreting genotype-by-environment Interactions through Transcriptome-Wide Interaction Analysis
4:30-4:45	Break
4:45-5:45	Session 4: Methods and Some Big Questions
Isabelle F. Foote Uncovering the multivariate genetic architecture of frailty using genomic structural equation modelling
Felix C. Tropf Finding the "missing environmentality"
Patrick Turley A General Approach to Adjusting Genetic Studies for Assortative Mating
5:45-6:00	Break
6:00-7:00	Keynote Address
Emily R. Klancher Merchant, PhD The American Pursuit of Intelligence Genes, 1916–2022

Time

Event

8:30-9:00

Coffee and Pastries

9:00-12:00

Statistical Genetics Workshop

Qiongshi Lu
Frontiers of PGS Construction, Optimization, and Use in the Social Sciences

12:00-1:00

Lunch

1:00-2:00

Session 1: Polygenic Indices Methods and Applications

Robel Alemu
Relative predictive performance of polygenic indexes (PGIs) across diverse ancestral populations

Silvia Helena Barcellos
Early-Life Determinants of Cognitive Decline and Dementia: The Role of Genetics and Education

Aysu Okbay
Polygenic Index Repository v2

2:00-2:15

Break

2:15-3:15

Session 2: Statistical Genetics Methods

Titus Galama
GWAS 2.0 – Correcting for volunteer bias in GWAS uncovers novel genetic variants and increases heritability estimates

Zhongxuan Sun
Pervasive biases in GWAS using family history of Alzheimer's disease as proxy phenotypes

Ramina Sotoudeh
Are we over-controlling for population stratification and discounting causal effects of genetic ancestry?

3:15-3:30

Break

3:30-4:30

Session 3: Frontiers in the Field of Genetics and Social Sciences

Jennifer Momkus
Socioepigenomics of Cellular Immunosenescence in Adulthood: The Add Health Study

Amadou Gaye
Transcriptome footprint of dietary sodium intake in African Americans

Jiacheng Miao
Quantifying and interpreting genotype-by-environment Interactions through Transcriptome-Wide Interaction Analysis

4:30-4:45

Break

4:45-5:45

Session 4: Methods and Some Big Questions

Isabelle F. Foote
Uncovering the multivariate genetic architecture of frailty using genomic structural equation modelling

Felix C. Tropf
Finding the "missing environmentality"

Patrick Turley
A General Approach to Adjusting Genetic Studies for Assortative Mating

5:45-6:00

Break

6:00-7:00

Keynote Address

Emily R. Klancher Merchant, PhD
The American Pursuit of Intelligence Genes, 1916–2022

Time	Event
8:30-9:00	Coffee and Pastries
9:00-10:15	Session 5: Gene-Environment Interactions
Dalton Conley The Portability of Within-Family PGIs
Pietro Biroli Beyond Barker: Infant Mortality at Birth and Ischaemic Heart Disease in Older Age
Yan Liu The Impact of the COVID-19 Pandemic on Mental Health and Its Interaction with Genetic Scores
10:15-10:30	Break
10:30-11:45	Session 6: Epigenetic Phenomena
Nicole Gladish Epigenetic aging as a mediator of racial and ethnic inequalities in mortality: results from the National Health and Nutrition Examination Survey, 1999-2002 mortality follow up study
Kathleen Mullan Harris Heterogeneous Consequences of Intergenerational Mobility for Biological Aging in Add Health
Aitor García The effect of childhood cultural capital on behavioral risks and health outcomes measured with GrimAge
11:45-1:00	Lunch
1:00-2:00	Session 7: Inheritance, Health, and Politics
Sven Oskarsson The genetics of political participation: Leveraging polygenic indices to advance political behavior research
Sjoerd van Alten A Chip Off the Old Block? Genetics and the Intergenerational Transmission of Wealth
Wei Zhao Genetic predisposition to depression and its impact on children and adolescents: the Panel Study of Income Dynamics
2:00-2:15	Break
2:15-3:15	Session 8: Genes, Environments, and Their Correlation
Marina Aguiar Palma Life's two lotteries: modeling the effects of genes and environments in human capital formation
Rafael Ahlskog Using fine-grained population based grid data to assess genetic self selection into residential neighborhoods across the lifespan
Brian Finch The Validity of Self-Rated Health for Mortality: Family-Background and Genetic Precursors
3:15-3:30	Closing Remarks and Discussion

Time

Event

8:30-9:00

Coffee and Pastries

9:00-10:15

Session 5: Gene-Environment Interactions

Dalton Conley
The Portability of Within-Family PGIs

Pietro Biroli
Beyond Barker: Infant Mortality at Birth and Ischaemic Heart Disease in Older Age

Yan Liu
The Impact of the COVID-19 Pandemic on Mental Health and Its Interaction with Genetic Scores

10:15-10:30

Break

10:30-11:45